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The Permian was a period of great blossoming for tetrapods.  Amphibians, anapsids, diapsids, and synapsids grew to great sizes.  Amphibians and anapsids reached sizes larger than they would ever be again, andt then the Diapsids took over.  This period was the end of large-sized synapsids until the extinction of the dinosaurs.  At the end of the Permian, a mass extinction wiped out 90% of all life on Earth.

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